Giuseppe Di Giovanni,Ennio Esposito,Vincenzo Di Matteo's 5-HT2C Receptors in the Pathophysiology of CNS Disease: 22 PDF

By Giuseppe Di Giovanni,Ennio Esposito,Vincenzo Di Matteo

a part of Springer’s “The Receptors,” sequence, this article is the 1st ever evaluation at the learn of 5-HT2c receptors. 5-HT2c receptor examine has been effective for twenty-five years, yet contemporary years have noticeable a unprecedented bring up in either quantity produced and perception received. 5-HT2c is a favourite principal serotonin receptor subtype commonly expressed in the crucial and the peripheral fearful method and is believed to play a key function within the rules of diverse behaviors. this article covers the molecular, mobile, anatomical, biochemical and behavioral facets of this receptor, highlighting its designated regulatory homes and the rising sensible importance of constitutive task and RNA-editing in vivo. It additionally investigates the receptors’ healing capability in lots of illnesses, taken care of separately in separate chapters, together with melancholy, drug abuse, schizophrenia, consuming issues, Parkinson’s sickness, Prader-Willi Syndrome, Alzheimer’s sickness and epilepsy.

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5-HT2C Receptors in the Pathophysiology of CNS Disease: 22 (The Receptors) by Giuseppe Di Giovanni,Ennio Esposito,Vincenzo Di Matteo


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